Journal Reviews

Prostaglandin versus leukotriene receptor-antagonists in treatment of seasonal allergic rhinitis RCT phase II

1 January 2018 | | Bayesian posterior probability, allergic rhinitis, leukotriene receptor antagonist, mast cell degranulation, prostaglandin D2 receptor 1 antagonist

Seasonal allergic rhinitis is very common. Failure to control the disease with mono-therapy leads to dual therapy treatment with less compliance and reduced quality of life. A prostaglandin receptor antagonist (ONO-4053) showed some efficacy in controlling allergic rhinitis in animal...